Early 19th century – A German physician, Justinus Kerner, began documenting cases of sausage poisoning or fatty poisoning. He discovered that the body can be poisoned from meat that are  improperly cooked or improperly handled. The word Botulus means sausage in Latin. Justinus Kerner as the first to devise the term botulism. 

1928  – P.T. Snipe and Hermann Sommer were able to successfully purify the toxin, opening it up for medical uses.

1949 –  Arnold Burgen was the first to discern that botulinum toxin (BTX) was actually a protein. He realized that it could interfere with the electrical activity of nerves and preventing them from acting as a neurotoxin. Since then, Anti Wrinkle has been used in the treatment of many medical conditions such as overactive bladders, migraines, neck pain, excessive underarm sweating, muscle spasms, eyelid spasms and stiffness or tightness of the muscles in the elbows, wrists, and fingers.

1989 – Dr. Richard Clark, a plastic surgeon, documented the effects of injecting of Anti Wrinkle into wrinkles. His study was published in Plastic and Reconstructive Surgery journals. 

1992 – J.D. and J.A. Carruthers, Canadian ophthalmologist and dermatologist respectively, had successful results after injecting Anti Wrinkle into the glabellar frown lines, the two lines between the eyebrows. Shortly, the U.S. Food and Drug Administration (FDA) approved Anti Wrinkle for use in the cosmetic aesthetic industry.

Anti Wrinkle is mainly used to even out fine lines and wrinkles in the forehead, glabellar lines, and crow’s feet around the eyes. The protein from the Anti Wrinkle hinders the nerve activities making it inactive once the Anti Wrinkle kicks in after a few days. The recipient may experience no side effects other than  some irritation at the injected areas, feeling of skin tightness after the procedure, and occasionally a tension headache. Day to day activities are resumed immediately, and the results last for 4 to 6 months. To maintain the desired look of smooth lines and no wrinkles, the patient can return on a regular basis for Anti Wrinkle injections.


Due to the popularity of Anti Wrinkle and its safe use, not only dermatologists and plastic surgeons are offering this procedure, but also the aesthetic salons and walk-in clinics. In 2014, the US alone had an estimated 7 million Anti Wrinkle treatments conducted. 

There are two solid competitors of Anti Wrinkle that sprung and certified for use which are Dysport and Xeomin. The differences are in the gradual onset and the longevity of the products. At Skin Club Cosmetics Doctors, we are pleased to offer these 3 anti-wrinkles injections. 

Dr. Vihang Sharma still highly recommends that patients do their research prior to selecting a clinic. Certified medical practitioners such as cosmetic doctors or dermatologists are the most trained professionals to administer Anti Wrinkle treatments.

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